The Selphyl

Selphyl® PRP Regenerative Medicine

The SELPHYL® System is designed for the safe and rapid preparation of autologous Platelet Rich Plasma (PRP) from a small sample of blood at the point of care. Many PRP systems require significant operator skill, produce varying results, and often have substantial contamination with red and white blood cells. SELPHYL® removes virtually all contaminating cells and does not depend on operator technique or experience. It is the next generation of PRP.

Why Selphyl Works So Well

Selphyl is ready when the body actually needs it delivering targeted growth factors precisely where healing is required.

Selphyl® PRP Regenerative Medicine

See it in action

See it in action

The Selphyl® Process

Blood Draw

Blood Draw

A small amount of the patient’s own blood is drawn into a vacuum collection tube containing a cell separator gel.

Centrifugation

Centrifugation

The tube spins for 6 minutes.

Transfer

Transfer

Platelets and plasma are transferred through a closed system.

Application

Application

The prepared PRP is ready for use as determined by the physician.

Selphyl® PRP (LP-PRP)

Selphyl® PRP (LP-PRP)

SELPHYL® PRP tube technology was the most consistent and reproducible system tested in an independent study from Stanford (Dragoo et al.). It produces leukocyte-poor and red blood cell-free PRP.

Low blood draw of 9–18 cc with a short spin time of 6 minutes
Closed system, preloaded with sodium citrate anticoagulant — no buffering required
Available in 4 cc and 8 cc PRP volumes
Up to 2-year shelf life

Is Platelet Rich Plasma Safe?

For over twenty years, PRP has been used across many fields of medicine. Research and clinical data confirm that PRP derived from a patient’s own blood is safe, with minimal risk of adverse reactions or complications.

Because it comes from your own blood, there is no risk of rejection or disease transmission. As with any injection, there is a very small risk of infection, but this is rare.

Peer-Reviewed Evidence

Selphyl is supported by multiple independent studies, including research from Stanford and other leading institutions.

Derived from the patient's own blood - no risk of rejection or disease transmission
Close to physiologic pH - no sodium bicarbonate buffering required before injection.
Contains no animal or synthetic products - virtually no risk of allergic reaction
The Selphyl System

The Selphyl® System

Single Kit (420910)

6 minutes - 4cc PRP

9ml blood draw
Double Kit (440910)

6 minutes - 8cc PRP

18ml blood draw

Centrifuge

Reasonable centrifuge program for your practice

References

1.

Dragoo JL, Braun HJ, Durham JL, et al. Comparison of the Acute Inflammatory Response of Two Commercial Platelet-Rich Plasma Systems in Healthy Male Volunteers. Am J Sports Med. 2012;40(6):1274-1281.

3.

Dragoo JL, Wasterlain AS, Braun HJ, Nead KT. Platelet-Rich Plasma as a Treatment for Patellar Tendinopathy: A Double-Blind, Randomized Controlled Trial. Am J Sports Med. 2014;42(3):610-618.

5.

Castillo TN, Pouliot MA, Kim HJ, Rosenwasser MP. Comparison of Growth Factor and Platelet Concentration from Commercial Platelet-Rich Plasma Separation Systems. Am J Sports Med. 2011;39(2):266-271.

7.

Mishra A, Pavelko T. Treatment of Chronic Elbow Tendinosis with Buffered Platelet-Rich Plasma. Am J Sports Med. 2006;34(11):1774-1778.

9.

Fitzpatrick J, Bulsara MK, McCrory PR, Richardson MD, Zheng MH. Analysis of Platelet-Rich Plasma Extraction: Variations in Platelet and Blood Components Between 4 Common Commercial Kits. Orthop J Sports Med. 2017;5(1).

11.

Kon E, Buda R, Filardo G, et al. Platelet-Rich Plasma: Intra-articular Knee Injections Produced Favorable Results on Degenerative Cartilage Lesions. Knee Surg Sports Traumatol Arthrosc. 2010;18(4):472-479.

Common Questions

Frequently Asked Questions

  • Selphyl PRP is an autologous Platelet Rich Plasma system that uses a small sample of your own blood to create a concentrated solution rich in growth factors. The process involves a quick blood draw, 6-minute centrifugation, and closed-system transfer to produce leukocyte-poor PRP ready for injection. This helps stimulate natural healing in injured or damaged tissues.

  • Selphyl stands out because it produces highly consistent, reproducible results with minimal red and white blood cell contamination. It does not rely heavily on operator technique, uses a closed system for safety, and requires no additional buffering. Independent studies, including research from Stanford, have shown it to be one of the most reliable PRP preparation methods available.

  • Yes. Because it is made from your own blood, there is no risk of disease transmission or allergic reaction. PRP has been used safely in medicine for over twenty years. The Selphyl system is FDA-cleared and designed to minimize contamination risks through its closed preparation process. As with any injection procedure, there is a small risk of infection, but this is rare.

  • Selphyl PRP is commonly used in orthopedic surgery, sports medicine, and musculoskeletal care. It can help patients with tendon injuries, osteoarthritis, ligament issues, fractures, and soft tissue conditions. Both physicians and patients can explore its use — contact us to see if it is suitable for your specific needs or practice.